# Authors

## Dr. Gao Feng

**Professor, School of Science, Tianjin University**  

[Author Profile](https://webofscience.clarivate.cn/wos/author/record/1506509)

Dr. Gao interests include **Computational Biology** and **Bioinformatics** with a special focus on microbial genomics and functional genomics. As the first author or corresponding author, he have published over 90 peer-reviewed papers in international journals, including **Nucleic Acids Research**, **PNAS**, **Briefings in Bioinformatics**, and **Bioinformatics**, and two book chapters in **Methods in Molecular Biology**. 

Dr. Gao developed web-based systems, such as **Ori-Finder** for the prediction of replication origins (oriCs) in microbial genomes, and **GC-Profile** for the visualization and analysis of GC content variation in genomic sequences. He also constructed online databases, such as **DoriC**, a database of oriC regions in both bacterial and archaeal genomes; **DeOri**, a database of eukaryotic DNA replication origins and **DEG 15**, an update of the Database of Essential Genes. Now, some of them are very popular with scientists in related fields. For example, Ori-Finder, which is cited over 200 times according to Web of Science, has been applied to annotate oriCs in hundreds of newly sequenced prokaryotic genomes including those published in Cell (Hackl et al., Cell, 2023) , Nature (Graf et al., Nature, 2021) and Nature Microbiology (Needham et al., Nature Microbiology, 2022), and has also been referred as software tool to identify replichores (Wannier et al., Nature Reviews Methods Primers, 2021). Currently, the predicted replication origins in dozens of bacteria and archaea have been confirmed by experiments, and our predictions have also been supported by the studies published in Science (Korem et al., Science, 2015) and Nature (Richardson et al., Nature, 2016).

Currently, Dr. Gao is a Faculty Member of **Faculty Opinions** (formerly F1000Prime) for Genomics & Genetics, the editorial board member of **Genome Biology**, **Briefings in Bioinformatics**, **Genomics, Proteomics & Bioinformatics**, **iMeta**, **BMC Microbiology**, **Scientific Reports**, **Microbiology Spectrum**, **PLoS ONE** and Associate Editor of Interdisciplinary Sciences: **Computational Life Sciences** and **Frontiers in Microbiology**.

## Dr. Lin Yan  

**Associate Professor, School of Science, Tianjin University**  

[Author Profile](https://webofscience.clarivate.cn/wos/author/record/2040017)

Dr. Lin is a dedicated researcher and educator in the fields of **Biophysics**, **Computational Biology**, and **Data Science**. Currently serving as an Associate Professor at Tianjin University’s School of Science, he combines cutting-edge research with a passion for teaching interdisciplinary courses such as *Computational Physics and Scientific Computing*, *Data Analysis Thinking*, *Physics Experiments and Error Theory*, *University Physics*, and *Fundamentals of Cloud Computing*.

His research contributions, published in high-impact SCI journals, reflect exceptional scholarly influence, with an average citation count exceeding 90 per paper and an h-index of 11 over the past five years (2024). Dr. Lin’s work bridges theoretical models and computational tools to address complex biological challenges, emphasizing innovation in bioinformatic data analysis and systems biology.

Actively engaged in the academic community, he holds memberships in prominent professional organizations, including the Functional Genomics Informatics and Systems Biology Branch of the Chinese Society for Cell Biology and the Biomedical Data Mining and Computing Committee of the China Society for Bioinformatics. Dr. Lin is committed to advancing scientific knowledge through collaborative research, mentorship, and the integration of computational methodologies into biological and physical sciences.

## Dr. Luo Hao

**Associate Professor, School of Science, Tianjin University**  

[Author Profile](https://webofscience.clarivate.cn/wos/author/record/472565)

Dr. Luo is an accomplished biophysicist and bioinformatics researcher currently serving as an Associate Professor at Tianjin University's School of Science. Holding a PhD in Biophysics, he specializes in the interdisciplinary fields of **Biological Physics** and **Bioinformatics**, with particular expertise in microbial genomics and bioinformatics database development. As an educator, Dr. Luo coordinates fundamental physics education through his courses in *University Physics* and *Physics Laboratory*, where he bridges theoretical concepts with practical experimental training.

His research program focuses on three key areas: (1) Bioinformatics algorithm development for microbial genome analysis; (2) Essential gene characterization and prediction systems; (3)Construction of specialized biological databases.Notable achievements include leading the **National Natural Science Foundation of China Youth Program** project *"Feature Analysis and Prediction of Human Essential Genes Based on Essential Gene Databases"*, recognized for its innovative approach to gene essentiality studies. His work has been honored with the **Excellent Paper Award at the National Postdoctoral Forum on AI Development and Applications**.

## Zhang Zetong

**Graduate Student, School of Science, Tianjin University**  

A student from Tianjin University.